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| l | RIPs can be
monomeric or |
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| heterodimeric,
generally AB |
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| l | The Heterodimer B
(“Binding”) Chain |
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| Interacts with
Cell Surfaces |
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| l | The Heterodimer
A (“Active”) Chain, or |
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| Monomer RIP,
Depurinates 28S rRNA |
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| » | A Conserved Stem
and Loop is Recognized |
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| » | An Adenine Base
in the Sequence GAGA |
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| is Hydrolyzed,
Inactivating the Ribosome |
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